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ADME DMPK Lead (Senior Scientist-Principal Scientist)

Remote, MA

Posted: 06/28/2022 Industry: Scientific and Life Sciences Job Number: 14560

Job Description

Connexion’s mission is to provide "best in class" services to job seekers. We strive to achieve excellence in job placement, staffing, and recruiting services, while treating candidates with the professionalism and respect they deserve.

Title: ADME DMPK Lead Scientist

Hiring Organization: Connexion Systems & Engineering

Compensation, Benefits, and Employment Type

  • Duration: PERM
  • Job Location: Fully Remote in 18 states (CA, CT, DE, FL, IL, IN, MA, MD, MI, NC, NH, NJ, NY, PA, RI, WA, WV)
  • Job#: bh14560

ADME DMPK Lead Scientist



  • Identify and implement appropriate assays and technologies relevant to ADME-DMPK characterization for assessment of small molecule therapeutics for the drug discovery portfolio.
  • Responsible for Discovery ADME study design, data analysis, PK/PD modeling & simulation and prediction.
  • Integrate, interpret and report data to project teams and management.
  • Initiate and facilitate collaboration with preclinical stakeholders for all DMPK/ADME projects.
  • Characterize routes of metabolism in vitro and in vivo.
  • Implement strategy and execution of non-clinical studies to identify DDI risks.



Required Qualifications


  • PhD in Pharmacokinetics, Drug Metabolism or related field, with at least 5 years industry experience evaluating small molecule therapeutics.
  • Hands on experience of detailed ADME/DMPK studies is essential.
  • An understanding of CNS therapeutic area is a plus.
  • Experience in identifying and characterizing DDI risks.
  • Experience in the outsourcing and external oversight of nonclinical DMPK/ADME studies conducted by qualified suppliers.
  • Excellent verbal and written skills, allowing for an open and effective dialogue throughout the company.
  • Attention to detail and quality are critical to success.
  • Highly accountable for the results and outcomes of their responsibilities and understands the impact of their efforts, results, and attitudes on others.
  • Uses teamwork to work cooperatively toward the most effective solutions, championing the best ideas of team members, and assisting where help is needed yet is capable of highly independent work when efficiency is required.
  • Results-oriented individual who is highly motivated, decisive, flexible in thought, and has the creativity to excel in and contribute to a rapidly growing company.
  • Forward thinking mindset with the ability to manage multiple projects, and identify and resolve issues.
  • Broad experience in an emerging, publicly traded company environment is a plus.



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Meet Your Recruiter

Alexandra (Scuncio) Pettit
Team Lead, Sr. Technical Recruiter

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