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Formulation Scientist - San Diego CA - 15060

San Diego, CA

Posted: 05/02/2022 Industry: Scientific and Life Sciences Job Number: 14331

Job Description

Connexion’s mission is to provide "best in class" services to job seekers. We strive to achieve excellence in job placement, staffing, and recruiting services, while treating candidates with the professionalism and respect they deserve.

Title: Senior Research Associate, Formulations

Hiring Organization: Connexion Systems & Engineering

Compensation, Benefits, and Employment Type

  • Duration: Temp-to-perm
  • Pay rate: $30/hr
  • Job Location: San Diego CA
  • Job#: bh14331

Senior Research Associate, Formulations

Seeking an inventive, well-organized research associate to join our Formulation Development group in San Diego, CA. As a member of Formulation Development team, this role will support to develop preformulations of small molecule chemical entities to support PK, pharmacology, and toxicology studies at our San Diego site. The candidate is expected to maintain Caco-2 cells and conduct the in vitro permeability assay to support drug candidate selection in early drug discovery. The candidate must be a strong team player with excellent communication skills working in a complex cross-functional matrix.

 

Experience in laboratory techniques commonly used in the analysis of preformulation such as HPLC, PXRD, TGA, DSC and cell culture experience are required.

 

 

 

Key Responsibilities:

 

Conduct material characterization (solubility, stability in bio-relevant media, permeability, physicochemical properties, form evaluations, etc) of candidate molecules

Develop solution and suspension formulation to support PK, Pharmacology and Toxicity studies

Assist on preliminary solid form screening for preclinical candidates

Maintain mammalian cells such as Caco-2, MDCK cells and generate the transwell plates and conduct in vitro permeability assay to support assessment of early drug discovery compounds

Help design, plan, execute, and interpret laboratory experiments to meet established project timelines.

Maintain laboratory equipment, keep instruments in good condition, and maintain stocks to prepare the preformulations

Maintain accurate and complete laboratory notebook capturing protocols, results and observations in real time

 

 

 

 

The successful candidate will possess:

 

Sound knowledge of pharmaceutical principles in the preformulation development with a range of dosage forms, including solution, suspension and IV formulations to support PK, pharmacology, and toxicology studies

Hands-on experience in analytical techniques such as HPLC methods, PXRD, TGA, DSC, and particle size analyses to enable evaluation of early-stage discovery compounds

Hands on experience in cell culture and in vitro permeability assay using Caco-2 cells

Excellent verbal and written communication skills

Successful and efficient multitasking and working as part of a multidisciplinary team that works within defined timelines

 

 

Minimum Qualifications

 

 

 

Bachelor’s or Master’s degree in chemistry, biochemistry, pharmaceutical science, or related field with 3+ years’ experience in pharmaceutical field

 

Please use the apply button to submit your resume for consideration. A Connexion Representative will contact you immediately.

 

When responding to this job posting you MUST include the Job# and Job Title in your subject line.

 

If you are active in a job search but this job is not for you, please reach out to jobpostings@csetalent.com. We would be glad to help you find the perfect job!

Meet Your Recruiter

Alexandra (Scuncio) Pettit
Team Lead, Sr. Technical Recruiter

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