Clinical Research Associate III
Posted: 07/06/2026
Industry: Scientific and Life Sciences
Job Number: 19290
Security Clearance: NA / not required
Job Description
Connexion’s mission is to provide "best in class" services to job seekers. We strive to achieve excellence in job placement, staffing, and recruiting services, while treating candidates with the professionalism and respect they deserve.
Title: Clinical Research Associate III
Hiring Organization: Connexion Systems & Engineering
Compensation, Benefits, and Employment Type
Description:
Our client is seeking an experienced Clinical Research Associate III to join its Clinical Operations team supporting Phase I oncology clinical trials. This is a sponsor-side role responsible for overseeing investigative sites, ensuring protocol compliance, protecting patient safety, and driving high-quality study execution.
This position is ideal for an experienced oncology CRA with direct early-phase (Phase I) monitoring experience who enjoys working collaboratively across cross-functional teams while serving as the primary sponsor representative for assigned study sites.
Responsibilities
Qualifications
Required:
Preferred:
If you're passionate about advancing innovative oncology therapies and thrive in a fast-paced clinical research environment, we'd love to hear from you. Apply today to learn more about this exciting contract opportunity.
Please use the apply button to submit your resume for consideration. A Connexion Representative will contact you shortly.
You may also send your resume and cover letter via email to the recruiter listed below. You MUST include the Job# and Job Title in your subject line.
If you are active in a job search but this job is not for you, please reach out to jobpostings@csetalent.com. We would be glad to help you find the perfect job!
Title: Clinical Research Associate III
Hiring Organization: Connexion Systems & Engineering
Compensation, Benefits, and Employment Type
- Duration: 1+ year contract, possible extension
- Pay rate: $50.02–$62.53/hour
- Job Location: Durham, NC (travel required)
- Schedule: Monday–Friday | 8:00 AM – 5:00 PM
- Job#: bh19290
Description:
Our client is seeking an experienced Clinical Research Associate III to join its Clinical Operations team supporting Phase I oncology clinical trials. This is a sponsor-side role responsible for overseeing investigative sites, ensuring protocol compliance, protecting patient safety, and driving high-quality study execution.
This position is ideal for an experienced oncology CRA with direct early-phase (Phase I) monitoring experience who enjoys working collaboratively across cross-functional teams while serving as the primary sponsor representative for assigned study sites.
Responsibilities
- Serve as the sponsor-side point of contact for assigned clinical trial sites.
- Conduct site qualification, initiation, routine monitoring, and closeout visits.
- Perform both onsite and remote monitoring in accordance with ICH-GCP, FDA regulations, study protocols, and sponsor SOPs.
- Oversee informed consent, patient eligibility, treatment administration, safety reporting, investigational product management, protocol deviations, and data quality.
- Evaluate site performance and proactively identify operational and quality risks.
- Escalate issues affecting patient safety, data integrity, compliance, or study timelines.
- Partner closely with Clinical Trial Managers, CROs, investigators, and cross-functional teams to resolve study issues.
- Review monitoring documentation and ensure inspection-ready study conduct.
- Support study startup activities, site activation, enrollment, and ongoing site engagement.
- Maintain strong relationships with investigators, research coordinators, pharmacists, nurses, and site personnel.
- Travel to investigative sites as needed.
Qualifications
Required:
- Bachelor's degree in Life Sciences, Nursing, Pharmacy, or a related scientific field preferred.
- Minimum 5 years of clinical monitoring experience.
- Direct Phase I oncology monitoring experience is required.
- Experience with dose-escalation studies and complex oncology protocols.
- Strong knowledge of ICH-GCP guidelines and FDA regulations.
- Experience using EDC, CTMS, eTMF, and other clinical trial systems.
- Excellent communication, organizational, and critical thinking skills.
- Ability to travel regularly for site monitoring.
Preferred:
- Sponsor-side or sponsor-dedicated CRA experience.
- Experience monitoring National Cancer Institute (NCI), cooperative group, or academic oncology studies.
- Experience collaborating with CRO partners and multidisciplinary clinical teams.
If you're passionate about advancing innovative oncology therapies and thrive in a fast-paced clinical research environment, we'd love to hear from you. Apply today to learn more about this exciting contract opportunity.
Please use the apply button to submit your resume for consideration. A Connexion Representative will contact you shortly.
You may also send your resume and cover letter via email to the recruiter listed below. You MUST include the Job# and Job Title in your subject line.
If you are active in a job search but this job is not for you, please reach out to jobpostings@csetalent.com. We would be glad to help you find the perfect job!
Meet Your Recruiter
Caroline Driscoll
Account Manager & Sr. Technical Recruiter
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